The friendship between two life-long girlfriends is put to the test when one starts a family and the other falls ill.
Paddy Considine, Dominic Cooper, Jacqueline Bisset, Drew Barrymore, Toni Collette, Noah Huntley, Tyson Ritter, Mehmet Ferda, Janice Acquah, Honor Kneafsey, Shola Adewusi, Lukas Rolfe, Charlotte Hope, Sophie Holland, Fjokra, Max Rinehart, Grace Schneider, Sophie Brown, Lucinda Raikes
Jess (Drew Barrymore) and Milly (Toni Collette) have been best friends forever. However, complications arise when Jess, who has been living a free-spirited existence, decides she wants a baby and begins to envy the life of Milly, a career woman with a family. In rapid succession, Milly is diagnosed with cancer and must battle for her life while Jess discovers she's finally pregnant. These life-changing events cause the friendship to be tested as they attempt to deal with the joy and sorrow in their lives.